Some of the compounds presented are investigational or are being investigated for uses that have not been approved by the US Food and Drug Administration (FDA), European Medicines Agency (EMA), or other health authorities.
Scientific Congress Publications
Supported by Bayer Pharmaceuticals
ESC 2026
Cardiac reverse remodelling of left heart during vericiguat therapy for high-risk HFrEF
- To characterise LV and LA reverse remodelling during 8 months of vericiguat therapy in adults with high-risk HFrEF after recent worsening HF.
- In adults with high-risk HFrEF after recent worsening HF, 8 months of vericiguat therapy was associated with LV reverse remodelling, improved LV deformation, and enhanced LA phasic function. These echocardiographic changes were accompanied by reductions in NT-proBNP and hs-cTnT and improvement in patient-reported health status.