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Some of the compounds presented are investigational or are being investigated for uses that have not been approved by the US Food and Drug Administration (FDA), European Medicines Agency (EMA), or other health authorities.

Scientific Congress Publications

Supported by Bayer Pharmaceuticals

ASN 2026

Finerenone in patients with focal segmental glomerulosclerosis: A FIND-CKD analysis

Finerenone slowed the progression of kidney function decline in participants with FSGS
 

  • Finerenone significantly slowed total eGFR decline from baseline to month 32 versus placebo

     

  • The effect was consistent between participants with primary and secondary FSGS

     

Finerenone showed favorable effects across clinical and urinary protein outcomes
 

  • Kidney and CV outcome HRs favored finerenone, but the differences were not nominally significant

     

  • Finerenone reduced UACR and UPCR at month 12

     

  • More participants achieved UACR <500 mg/g and UPCR <700 mg/g at month 12 with finerenone than with placebo
     

Finerenone was well tolerated, with a safety profile broadly comparable to placebo
 

  • Overall rates of TEAEs, including hyperkalemia, were similar between treatment groups

     

  • Serious TEAEs were not more frequent with finerenone, and no fatal TEAEs occurred